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Prevention of scar hyperplasia in the skin by conotoxin: A prospective review
Author(s) -
Sun Pengfei,
Ji Zhonglei,
Li Zhengyong,
Pan Bo
Publication year - 2021
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13761
Subject(s) - medicine , hyperplasia , scars , botulinum toxin , dermatology , wound healing , surgery , pathology
Scars are often considered to be skin problems that affect beauty. The tension acting on the edge of the wound is the main factor causing the scar hyperplasia. At present, the clinical use of botulinum toxin A (BTX‐A) around the wound to cause transient muscle paralysis reduce the muscle movement around the wound and wound tension to prevent scar hyperplasia during wound healing. But the use of BTX‐A to prevent scarring requires the use of a syringe. The syringe can cause trauma and pain when it pricks the skin for BTX‐A injection. The conotoxin which is secreted by the poison glands on the inside of the venom tube and capsule of the snail provides a simple and effective way to prevent skin scar hyperplasia. We reviewed the classification of conotoxin, the conotoxin's mechanism of preventing scar hyperplasia, and the research direction of conotoxin in the future and provided reference for promoting the application of conotoxin in preventing skin scar hyperplasia.