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Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow’s feet, and collagen content: A double‐blind, randomized, placebo‐controlled trial
Author(s) -
Lin Ping,
Alexander Ruth Audy,
Liang ChiaHua,
Liu Cheng,
Lin YungHao,
Lin YungHsiang,
Chan LeongPerng,
Kuan ChenMeng
Publication year - 2021
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13500
Subject(s) - placebo , medicine , skin aging , double blind , dermatology , surgery , pathology , alternative medicine
Background The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect is not in place. Aim This clinical study is to investigate the synergistic effect of fish collagen and Djulis ( Chenopodium formosanum Koidz.) for improvement of skin parameters. We used the combination of hydrolyzed collagen and Djulis to develop a new functional formula for skin improvement. Patients/Methods Fifty volunteers were randomly allocated (in a 1:1 ratio) to the placebo or collagen drink group. Volunteers were required to consume a 50 mL of a collagen drink or placebo drink daily for 8 weeks. For measurements, the indexes of skin conditions were measured at the baseline and 4 and 8 weeks. Results The improvements of skin hydration, brightness, crow's feet, texture, wrinkles, pores, spots, and collagen content after 8 weeks in collagen group were 17.8%, 5.4%, 14.9%, 9.9%, 29.3%, 10.4%, 9.9%, and 22.3%, respectively. Noticeably, over 68% of subjects got improved for their skin parameters after 8‐week intake of collagen drink. The improvement levels indicated competitive skin improvement effects in comparison with previous studies. Conclusion This clinical study demonstrates the synergistic effect of fish collagen and Djulis (the main components) for the substantial improvements in hydration, brightness, crow's feet, texture, wrinkles, pores, surface spots, and collagen content in skin. The collagen drink comprehensively improved skin parameters for most subjects after 4‐week intake and manifested competitive efficiency in comparison with other similar studies. We convince that the collagen drink may delay skin aging process and improve skin aging parameters.