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Efficacy of olive leaf extract–containing cream for facial rejuvenation: A pilot study
Author(s) -
Wanitphakdeedecha Rungsima,
Ng Janice Natasha C.,
Junsuwan Natchaya,
Phaitoonwattanakij Sutasinee,
Phothong Weeranut,
Eimpunth Sasima,
Manuskiatti Woraphong
Publication year - 2020
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13457
Subject(s) - transepidermal water loss , erythema , medicine , wrinkle , olive oil , dermatology , oleuropein , rejuvenation , photoaging , food science , surgery , chemistry , stratum corneum , gerontology , pathology
Background Olive leaf extract (OLE), a naturally extracted product from olive leaves, contains oleuropein and other bioactive phenolic compounds. Oleuropein was identified to have various medical properties. It was also found to inhibit the effects of both acute and chronic UVB‐induced skin damage as well as accelerate wound healing activity. Aims To evaluate the efficacy of olive leaf extract–containing cream on facial rejuvenation. Methods This is a prospective pilot study with a total of 36 participants, who presented with photoaging skin. All participants applied the olive leaf extract–containing cream (SUPERHEAL™ O‐Live Cream, PhytoCeuticals, Inc, USA) to their whole face twice daily for 2 months. Primary outcomes measured in the study were the changes in the biophysical properties of the skin assessed with the following parameters: melanin and erythema index, transepidermal water loss (TEWL), skin hydration, skin pH, sebum level, texture, and wrinkles. Results After 2 months, TEWL decreased significantly ( P = .007) and maintained the results 1 month after discontinuation of the treatment ( P = .007). Skin hydration also increased significantly after 2 months ( P = .004). Wrinkles improved significantly on all follow‐ups ( P < .001, P = .001, P = .001, respectively). An image of the skin captured using Visioscan® showed improvement of the skin texture 2 months after treatment. Majority of the participants (64%) noted improvement in their skin texture. Conclusion Olive leaf extract–containing cream provided benefits on skin rejuvenation in human skin.