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Update in minimally invasive periorbital rejuvenation with a focus on platelet‐rich plasma: A narrative review
Author(s) -
Kassir Martin,
Kroumpouzos George,
Puja Priya,
Katsambas Andreas,
Galadari Hassan,
Lotti Torello,
Abdelmaksoud Ayman,
Grabbe Stephan,
Juchems Eva,
Goldust Mohamad
Publication year - 2020
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13376
Subject(s) - rejuvenation , modalities , facial rejuvenation , platelet rich plasma , medicine , dermatology , narrative review , medline , treatment modality , surgery , intensive care medicine , biology , platelet , social science , biochemistry , sociology
Background The periorbital region is among the first areas to be affected by the process of aging, which is influenced by genetic and constitutional factors. As the region plays an important role in overall facial appearance, rejuvenation of the area has immense cosmetic benefit and various treatment modalities have been used to achieve the same. Aims This article reviews commonly used non‐surgical and minimally invasive modalities for periorbital rejuvenation. Methods The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Only articles available in English were considered for this review. Results Autologous platelet rich plasma (PRP) is increasingly used in dermatology for skin and hair conditions. The use of PRP is rapidly growing in popularity as a modality to achieve skin rejuvenation. The mechanism by which PRP leads to skin rejuvenation is by increasing the dermal fibroblast proliferation, expression of matrix metalloproteinase and collagen synthesis. Conclusion The evidence discussed in this article indicates the increasing importance of minimally invasive modalities in periorbital rejuvenation and a promising role for PRP as solo therapy or in multimodality regimens.

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