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Soft tissue distribution pattern of facial soft tissue fillers with different viscoelastic properties
Author(s) -
Rosamilia Gianna,
Hamade Hassan,
Freytag David L.,
Frank Konstantin,
Green Jeremy B.,
Devineni Aditya,
Gavril Diana L.,
Hernandez Claudia A.,
Pavicic Tatjana,
Cotofana Sebastian
Publication year - 2020
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13246
Subject(s) - soft tissue , zygomatic arch , forehead , materials science , viscoelasticity , biomedical engineering , composite material , anatomy , medicine , surgery
Background Soft tissue filler product distribution and tissue integration have been shown to depend on myriad factors including the injector type, injector size, and injection angle. Aim This study aims to investigate the magnitude of product spread across fascial soft tissue layers in relation to product viscoelastic properties. Patients/Methods A total of 168 injection procedures were conducted in two female Caucasian body donors with a mean age of 80 years (range: 79‐81) and a mean body mass index of 23.6 kg/m 2 (range: 21.0‐26.6). The injection procedures were performed in the forehead, scalp, zygomatic arch, mandible, clavicle, and sternum. The injected materials included Belotero ® Soft, Belotero ® Balance, Belotero ® Intense, Belotero ® Volume, Radiesse ® , and Radiesse ® Plus. Layer‐by‐layer dissections were performed to investigate the vertical distribution of the injected product. Results The mean product spread was for Belotero ® Soft 4.54 ± 0.91; Belotero ® Balance 3.85 ± 1.19; Belotero ® Intense 3.04 ± 1.34; Belotero ® Volume 2.58 ± 1.27; Radiesse ® 1.31 ± 0.47; and Radiesse ® Plus 1.27 ± 0.45 with P < .001. Bivariate correlations between product spread and storage modulus (G’) revealed an inverse relationship of moderate strength with r p = −0.651 and P < .001. Conclusion The results of the present study revealed that products that were more fluid and less viscous distributed into more superficial fascial layers than products that were less fluid and more viscous ( P < .001). This relationship held true irrespective of injected location.