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Lower facial regeneration with a combination of platelet‐rich fibrin liquid matrices based on the low speed centrifugation concept‐Cleopatra technique
Author(s) -
Nacopoulos Cleopatra,
Vesala AnnaMaria
Publication year - 2020
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.13196
Subject(s) - cleopatra , fibrin , centrifugation , medicine , surgery , platelet rich fibrin , chemistry , chromatography , art , literature , immunology
Background Autologous blood concentrates are increasingly being applied in esthetic medicine and dentistry due to their safety and their potential beneficial properties. Platelet‐rich fibrin based on the low speed centrifugation, a newly described blood product, seems to convey additional properties in several in vitro and ex vivo studies. Its clinical significance however in relation to facial regeneration remains anecdotal. Objective The aim of this study was to assess a specific combination of PRF liquid matrices utilized for lower facial regeneration (Cleopatra technique). Patients/Methods Cleopatra technique was applied in 32 patients. In addition to recording of all patients' complaints and adverse events, a photographical study was performed. Possible positive effects were assessed by asking twenty‐three independent reviewers to distinguish initial and later photographs of each patient. Results A statistically significant percentage of true answers by the reviewers was noted upon completion of the treatment ( U = 110.5, P < .001), which indicates a clinically significant effect of Cleopatra technique. Moreover, only few minor, self‐limited adverse events were recorded. Conclusions Cleopatra technique is a well‐tolerated and effective method of lower facial rejuvenation that deserves further attention from dentists and other health professional who utilize conservative methods in facial esthetics.