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Open‐label study assessing the efficacy and tolerability of topical skin care and sun protection alone and in combination with intense pulsed light therapy
Author(s) -
Deaver Peterson Jennifer,
Katz Tracy M.
Publication year - 2019
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12952
Subject(s) - erythema , intense pulsed light , tolerability , medicine , itching , dermatology , rosacea , regimen , adverse effect , surgery , acne
Background Intense pulsed light therapy (IPL) decreases facial erythema and telangiectasias associated with rosacea. Topical skin care products decrease facial erythema by the action of active ingredients and masking effects. Objectives To assess the efficacy and tolerability of combining a topical skin care regimen (TSCR) comprised of a multifunctional three‐in‐one facial cream and a mineral‐based brush‐on SPF50 powder sunscreen with a single IPL treatment for treating mild‐to‐severe facial redness associated with rosacea. Methods Twenty female subjects with Fitzpatrick skin types I‐III received TSCR monotherapy for 12 weeks. At that time, subjects received a single IPL treatment and continued TSCR for 6 additional weeks. Subjects were evaluated at Baseline and at Weeks 4, 8, 12, and 18. Results Using a 7‐point redness scale, the overall mean (SD) redness score significantly improved from 3.05 (0.97) at baseline to 2.05 (0.76) at Week 18 ( P < 0.01). There was a decrease in investigator‐rated erythema from baseline (bare skin) to Week 12 (bare skin, before IPL) when TSCR was used as monotherapy which did not achieve significance ( P = 0.12). Most subjects (80%) were satisfied or Very satisfied with the TSCR at Week 18. All subjects (100%) agreed that it improved their baseline skin redness and most (85%) would recommend TSCR to others. TSCR was well‐tolerated with no significant changes in skin dryness, scaling, or itching. Mild burning occurred immediately following the IPL treatment at Week 12. Conclusion TSCR in combination with a single IPL treatment produced a significant improvement in overall facial redness in patients with rosacea. Longer‐term treatment with TSCR may produce continued improvement.