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Efficacy of microneedling with topical vitamin C in the treatment of melasma
Author(s) -
Ismail Esraa Salah Ali,
Patsatsi Aikaterini,
Abd elMaged Wafaa Mohammed,
Nada Essam ElDin Abd elAziz
Publication year - 2019
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12878
Subject(s) - melasma , medicine , dermatology
Summary Background Despite the wide therapeutic options available for the treatment of melasma, including many active topical medications, technologies with lights and peelings, clinical control of this disorder is extremely challenging. Objectives To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma. Methods Thirty female patients with melasma received six sessions of microneedling with addition of topical vitamin C every two weeks. At each session, photos were taken and Melasma Area and Severity Index (MASI) score was calculated to assess the clinical improvement. Results Mean age of the eligible patients was 33.2 ± 5.77 years. About 50% of cases were of Fitzpatrick skin type III. All patients showed improvement at the end of the sessions. Mean MASI score in the first session was 8.61 ± 4.45 and there was a gradual decline in its value till it reached a mean of 5.75 ± 4.16 in the last session ( P < 0.0001). Conclusion Microneedling with topical vitamin C is an effective and safe treatment option for epidermal melasma especially in Fitzpatrick skin phototypes I‐III.