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Comparison of novel dual mode vs conventional single pass of a 1450‐nm diode laser in the treatment of acne vulgaris for Korean patients: A 20‐week prospective, randomized, split‐face study
Author(s) -
Kwon Hyuck Hoon,
Choi Sun Chul,
Jung Jae Yoon,
Bae You In,
Park GyeongHun
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12788
Subject(s) - acne , medicine , regimen , hyperpigmentation , acne treatment , randomized controlled trial , patient satisfaction , surgery , dermatology
Summary Background Although a 1450‐nm diode laser has been shown to be effective for acne, the conventional high‐energy stamp‐only regimen is often associated with pain and hyperpigmentation, especially for dark‐skinned individuals. Aims To evaluate whether the novel dual regimen has clinical advantages for acne treatments compared with conventional regimen in Asian patients. Patients and Methods Twenty‐four Korean patients with facial acne were treated with a 1450‐nm diode laser through a 20‐week, randomized, split‐face study. The patients were treated with three consecutive sessions at 4‐week intervals. One half of the face received a dual regimen consisting of low‐fluence stamping mode (5‐6 J/cm 2 ) for inflammatory acne lesions only, followed by 4‐5 passes of moving mode for the full face. The other side received a single‐pass treatment of conventional high‐fluence stamp mode (14‐15 J/cm 2 ). Evaluations for acne, sebum secretion measurements, and safety profiles were performed. Results At the final 12‐week follow‐up evaluations, the dual‐mode side demonstrated better improvements in both inflammatory and noninflammatory lesion counts, acne severity assessments, and reduction in sebum secretion compared with stamp‐only side. Subjective satisfaction for the improvement for acne, seborrhea, and texture correlated well with objective assessments. In addition, degrees of pain and treatment‐related side effects were remarkably decreased in the novel dual mode. Conclusion This novel dual regimen of the 1450‐nm laser demonstrated improved efficacies for acne and seborrhea with satisfactory safety profiles. Therefore, this regimen would be a viable option for acne treatments either as monotherapy or as combination therapy.