Cervical lymphadenopathy from PRP treatment with microneedling therapy

Background Platelet‐rich plasma is highly enriched plasma that contains a large concentration of platelets that secrete various growth factors and is used in a wide variety of surgical and cosmetic procedures, including hair regrowth and skin rejuvenation. Methods Microneedling therapy is being combined with platelet‐rich plasma to potentiate patient's cosmetic effects. While microneedling therapy and platelet‐rich plasma therapy have been around for years and are growing in popularity internationally, there are limited data regarding complications when they are used in conjunction. Results We present a case in which a patient presented with acute, painful lymphadenopathy shortly after undergoing the combination treatment of a microneedling pen with platelet‐rich plasma therapy. Conclusion Individuals should know of the potential adverse effect of microneedling pen therapy used in conjunction with platelet‐rich plasma therapy, and it should be included in patient consent forms and doctor–patient education.