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Applications and efficacy of platelet‐rich plasma in dermatology: A clinical review
Author(s) -
Zhang Meijie,
Park Gajin,
Zhou Bingrong,
Luo Dan
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12673
Subject(s) - vitiligo , medicine , dermatology , platelet rich plasma , randomized controlled trial , clinical trial , alopecia areata , facial rejuvenation , surgery , platelet , pathology
Summary The platelet‐rich plasma ( PRP ) has been studied in bone‐related applications for accelerating healing, and the proliferation and regeneration of tissue. Now the dermatological indications increase rapidly in recent years. We have reviewed clinical trials, comparative trials, and meta‐analysis of PRP on dermatology through key words and reorganized them into facial rejuvenation, hair, scar, vitiligo, and synergistic effect with fractional CO 2 , with a conclusion that PRP has significant improvements in dermatology. But the lack of RCT s and the limit of samples cannot provide sufficient enough evidence for general clinical applications. More RCT s are needed for the increasing demand of new dermatologic therapeutics, and we need adequate samples urgently to make the results more persuasive.