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Effect of age and body mass index on the yield of stromal vascular fraction
Author(s) -
Alaaeddine Nada,
El Atat Oula,
Saliba Nagib,
Feghali Ziad,
Nasr Marwan,
Tarabey Bilal,
Hilal George,
Hashim Hussein
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12458
Subject(s) - stromal vascular fraction , body mass index , medicine , stem cell , liposuction , yield (engineering) , abdomen , adipose tissue , surgery , pathology , biology , materials science , metallurgy , genetics
Summary Objective The aim of this study was to determine the influence of age, body mass index, and site of liposuction on the cell yield of SVF . Methods A prospective study was performed on 58 patients. The average age was 39 years old, with BMI ≤ 25 or BMI ≥ 25. Fat tissue was harvested from the abdominal region, flanks, or thighs and SVF was isolated. Results The yield of viable SVF was evaluated by trypan blue, and the markers of stem cells were evaluated by flow cytometry. The cells were positive for stem cells markers, the age, sex of the patient had no impact on SVF cell yield with an average of 1.17 × 10^8. However, the BMI > 25 had resulted in higher cell numbers, and the harvest site had a significant impact on cell yield with abdomen being the site of interest. Conclusion These data demonstrate that the age of the person does not affect the cell yield of SVF ; nevertheless, the donor site and BMI might be important factors in affecting cell number.