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Cross‐sectional study of the microbiological safety profile of reusing hyaluronic acid fillers
Author(s) -
Pontello Rubens,
Kondo Rogério Nabor,
Pavezzi Priscila Daiane,
Nicolacopulos Theo,
Kippert Julia Pagung,
Lena Clarissa
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12364
Subject(s) - hyaluronic acid , cross sectional study , safety profile , medicine , dentistry , adverse effect , pharmacology , pathology , anatomy
Summary Introduction Facial filling with hyaluronic acid ( HA ) is a dermatological procedure that has been emerging today. There are not many references regarding safety of reusing the remaining product for later touch‐up in the same patient. Objective To determine the microbiological safety of reusing hyaluronic acid that is remnant from syringes used for facial filling, stored at room temperature or cooled in a refrigerator at 4°C. Materials and methods In culture medium, small aliquots of leftovers from 31 hyaluronic acid fillers, previously used for facial filling, were inoculated. The fillers were stored in their original syringes at room temperature or cooled in a standard refrigerator at 4°C for a period ranging from 1 week to 12 months after initial use. Limitations The small number of samples limits extrapolation of the results obtained. Results After 42 days of inoculation in culture medium, none of the samples showed any aerobic or anaerobic bacterial or fungal growth. Conclusion Hyaluronic acid fillers did not show any fungal or bacterial contamination after being opened and stored at room temperature in nonaseptic conditions. The possibility of reusing the remaining portion of the material in the syringe can be safe and economically viable.