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Acneiform eruptions caused by vitamin B12: A report of five cases and review of the literature
Author(s) -
Veraldi Stefano,
Benardon Susanna,
Diani Marco,
Barbareschi Mauro
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12360
Subject(s) - medicine , vitamin b12 , discontinuation , dermatology , shoulders , folliculitis , glossitis , surgery , pathology , tongue
Summary We describe five cases of acneiform eruption caused by vitamin B12 in five females aged 37, 32, 62, 29, and 21 years, respectively. The eruption appeared from 1 week to 5 months after the beginning of the therapy with i.m. or oral vitamin B12. Clinical picture was characterized by papules and pustules located on the face. In three patients, similar lesions were also present on the neck, shoulders, chest, and upper portion of the back. Comedones and cysts were absent. In two patients, serum vitamin B12 levels were very high. Histopathologic examination in one patient revealed an eosinophilic folliculitis. Spontaneous and complete remission was observed in all patients 3‐6 weeks after vitamin B12 discontinuation.