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The efficacy of a lip balm containing pseudo‐ceramide on the dry lips of sensitive skin‐conscious subjects
Author(s) -
Isoda Keiichi,
Nakamura Tadashi,
Yoshida Kensuke,
Tamura Eiko,
Atsuta Nami,
Ishida Koichi,
Takagi Yutaka,
Mizutani Hitoshi
Publication year - 2018
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12351
Subject(s) - stratum corneum , dry skin , medicine , ceramide , dermatology , upper lip , adverse effect , chemistry , pathology , anatomy , apoptosis , biochemistry
Summary Background Many people use lip care products daily to prevent dry lips. However, some people, especially those with sensitive skin‐consciousness, complain of various skin problems on their lips including contact dermatitis caused by lip care products. Dry lips have decreased water holding capacity and cutaneous barrier function as well as reduced stratum corneum ceramide levels. In this study, we investigated the usefulness of a newly formulated lip balm containing pseudo‐ceramide for the dry lips of subjects with sensitive skin. Method Thirty subjects with dry lips and sensitive skin‐consciousness used the test lip balm more than twice a day for 4 weeks. Lip conditions were evaluated before and after 2 and 4 weeks. Result Visual evaluation by a dermatologist showed that overall improvements were observed in all subjects as early as week 2. After 4 weeks of usage, 27% of the subjects were objectively judged as “markedly improved” and 60% of the subjects were judged as “improved”. No adverse event developed throughout the test period, and all subjects were able to use the lip balm safely for 4 weeks. Usefulness was judged based on all evaluation items, and 27%, 70%, and 3% of the subjects were judged as “very useful,” “useful,” and “slightly useful,” respectively. Ninety percentage of the subjects expressed improvement and acceptance of the lip balm. Conclusion Based on these results, the newly formulated lip balm containing pseudo‐ceramide is very useful for the lip care of sensitive skin‐conscious subjects as well as for daily use by healthy subjects.