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Serum collagenase‐2 and BMI levels in pregnant women with striae gravidarum
Author(s) -
Ozturk Perihan,
Kıran Hakan,
Kurutas Ergul Belge,
Mulayim Kamil,
Avcı Fazıl
Publication year - 2017
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12269
Subject(s) - medicine , collagenase , pregnancy , body mass index , etiology , hormone , obstetrics , endocrinology , physiology , biology , enzyme , biochemistry , genetics
Summary Objective Striae gravidarum is a form of scarring on the skin observed during pregnancy and can cause serious cosmetic problems. Striae gravidarum may be influenced by hormonal changes, although the etiology is not clear. The aim of this study was to investigate whether body mass index ( BMI ) and serum collagenase‐2 levels in pregnant women are related to the development of striae gravidarum. Methods Thirty pregnant women with striae, 30 pregnant women without striae, and 32 health controls were enrolled in the study. Results BMI and serum collagenase‐2 levels were measured in the participants. Conclusion Pregnant women with striae gravidarum had increased serum collagenase‐2 and BMI levels when compared to pregnant women without striae gravidarum and healthy controls ( P < 0.05). The increase in serum collagenase‐2 levels was related to the development of striae gravidarum alone, or secondary to BMI increase.