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What do we know about sulforaphane protection against photoaging?
Author(s) -
Sikdar Sohely,
Papadopoulou Maria,
Dubois Jacques
Publication year - 2016
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12176
Subject(s) - sulforaphane , photoaging , skin aging , cruciferous vegetables , antioxidant , reactive oxygen species , chemistry , cosmetics , matrix metalloproteinase , skin cancer , ingredient , pharmacology , food science , cancer , medicine , biochemistry , dermatology , organic chemistry
Summary Sulforaphane ( SFN ), a natural compound occurring in cruciferous vegetables, has been known for years as a chemopreventive agent against many types of cancer. Recently, it has been investigated as an antioxidant and anti‐aging agent, and interesting conclusions have been made over the last decade. SFN demonstrated protective effects against ultraviolet ( UV )‐induced skin damage through several mechanisms of action, for example, decrease of reactive oxygen species production, inhibition of matrix metalloproteinase expression, and induction of phase 2 enzymes. SFN used as a protective agent against UV damage is a whole new matter, and it seems to be a very promising ingredient in upcoming anti‐aging drugs and cosmetics.