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The effect of CO 2 laser treatment on skin tissue
Author(s) -
Baleg Sana Mohammed Anayb,
Bidin Noriah,
Suan Lau Pik,
Ahmad Muhammad Fakarruddin Sidi,
Krishnan Ganesan,
Johari Abd Rahman,
Hamid Asma
Publication year - 2015
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12142
Subject(s) - laser , dermis , epidermis (zoology) , materials science , irradiation , photothermal therapy , dorsum , biomedical engineering , ex vivo , in vivo , chemistry , dermatology , biophysics , optics , anatomy , medicine , nanotechnology , biology , physics , nuclear physics , microbiology and biotechnology
Summary Background/Objective The aim of this study was to evaluate the effects of multiple pulses on the depth of injury caused by CO 2 laser in an in vivo rat model. Methods A 10 600‐nm CO 2 laser was applied to rat skin, with one side of the rat dorsal skin being exposed, leaving the other side as a control. Results All of the various laser pulses tested led to gradual loss of epidermal thickness as well as a dramatic increase in thermal damage depth. Collagen coagulation was most effective with ten pulses of CO 2 laser, while the strength of irradiated skin tissue increased as the influence of the laser increased. Conclusion Fundamental laser–skin interaction effects were studied using a CO 2 laser. The photodamaged areas obtained from laser interaction were recorded via couple charge device video camera and analyzed via ImageJ software. Photodamage induced by CO 2 laser is due to photothermal effects, which involve burning and vaporizing mechanisms to ablate the epidermis layer. The burning area literally expands and penetrates deep into the dermis layer, subsequently causing collagen coagulation. This fundamental study shows in detail the effect of CO 2 laser interaction with skin. The CO 2 attributed severe burning, producing deep coagulation, and induced strength to treated skin.