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Effect of a nutritional supplement on hair loss in women
Author(s) -
Le Floc'h Caroline,
Cheniti Ahsène,
Connétable Sophie,
Piccardi Nathalie,
Vincenzi Colombina,
Tosti Antonella
Publication year - 2015
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12127
Subject(s) - hair loss , medicine , hair growth , clinical endpoint , randomized controlled trial , dermatology , physiology
Summary Background Female pattern hair loss is a frequent and distressing condition. Aim To evaluate vs . control, the effects on hair loss of a 6‐month supplementation with specific omega 3&6 and antioxidants. Methods One hundred and twenty healthy female subjects participated in this 6‐month, randomized, comparative study. The primary endpoint was the change in hair density evaluated on standardized photographs. Secondary endpoints included changes in telogen hair percentage and diameter distribution of anagen hair (>40 µm vs . ≤40 µm) measured by trichogram. Overall changes in hair density and diameter were also measured by trichometer and by subjects’ self‐assessment. Results After 6 months of treatment, photograph assessment demonstrated a superior improvement in the supplemented group ( P < 0.001). The telogen hair percentage was significantly ( P < 0.001) reduced in the supplemented group. The proportion of nonvellus anagen hair (>40 µm) increased compared to the control group. The trichometer index increased in the supplemented group, while it decreased in the control group. A large majority of supplemented subjects reported a reduction in hair loss (89.9% of subjects at 6 months), as well as an improvement in hair diameter (86.1%) and hair density (87.3%). Conclusion A 6‐month supplementation with omega 3&6 and antioxidants acts efficiently against hair loss in improving hair density and reducing the telogen percentage and the proportion of miniaturized anagen hair. Objectively measured improvements were confirmed by the subjects’ perception of efficacy.