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Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4)
Author(s) -
Abels Christoph,
Reich Hubert,
Knie Ulrich,
Werdier Dieter,
Lemmnitz Gunter
Publication year - 2014
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/jocd.12086
Subject(s) - tolerability , acne , medicine , glycolic acid , dermatology , clinical trial , acne treatment , adverse effect , lactic acid , biology , bacteria , genetics
Summary Background Cleansing products for acne should remove excessive sebum, reduce acne‐related bacteria and improve inflammation. Aims The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. Methods Sixty patients were recruited for this open uncontrolled clinical trial. The tested product was exclusively applied twice a day for 6 weeks. The efficacy was judged by a dermatologist according to the Leeds score after 3 and 6 weeks. In addition, efficacy and tolerability were judged subjectively by physician and patients. Results Mild acne improved significantly after 6 weeks (baseline: 0.699 vs . day 42: 0.602; P < 0.001). Efficacy and tolerability were judged better by physician as compared with patients' assessment. Conclusion In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice‐daily application for 6 weeks as monotherapy.