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Anatomical map of the cranial vasculature and sensory ganglia
Author(s) -
Taberner Laura,
Bañón Aitor,
Alsina Berta
Publication year - 2018
Publication title -
journal of anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 118
eISSN - 1469-7580
pISSN - 0021-8782
DOI - 10.1111/joa.12762
Subject(s) - anatomy , autonomic ganglion , hindbrain , sensory system , ganglion , biology , cranial nerves , zebrafish , neuroscience , nervous system , central nervous system , biochemistry , gene
There is growing evidence of a direct influence of vasculature on the development of neurons in the brain. The development of the cranial vasculature has been well described in zebrafish but its anatomical relationship with the adjacent developing sensory ganglia has not been addressed. Here, by 3D imaging of fluorescently labelled blood vessels and sensory ganglia, we describe for the first time the spatial organization of the cranial vasculature in relation to the cranial ganglia during zebrafish development. We show that from 24 h post‐fertilization (hpf) onwards, the statoacoustic ganglion ( SAG ) develops in direct contact with two main blood vessels, the primordial hindbrain channel and the lateral dorsal aortae ( LDA ). At 48 hpf, the LDA is displaced medially, losing direct contact with the SAG . The relationship of the other cranial ganglia with the vasculature is evident for the medial lateral line ganglion and for the vagal ganglia that grow along the primary head sinus ( PHS ). We also observed that the innervation of the anterior macula runs over the PHS vessel. Our spatiotemporal anatomical map of the cranial ganglia and the head vasculature indicates physical interactions between both systems and suggests a possible functional interaction during development.