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Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle
Author(s) -
ZellerPlumhoff B.,
Roose T.,
Katsamenis O. L.,
Mavrogordato M. N.,
Torrens C.,
Schneider P.,
Clough G. F.
Publication year - 2017
Publication title -
journal of anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 118
eISSN - 1469-7580
pISSN - 0021-8782
DOI - 10.1111/joa.12606
Subject(s) - skeletal muscle , soleus muscle , anatomy , muscle spindle , phase contrast microscopy , neurovascular bundle , tomography , biology , medicine , physics , radiology , afferent , optics
Muscle spindles are skeletal muscle sensory organs involved in the sensation of position and movement of the body. We have explored the capability of phase contrast computed tomography to visualise muscle spindles in murine skeletal muscle. In particular, we have validated the visualisation of nerve fibres through phase contrast computed tomography using light microscopy on stained histological sections. We further present the first three‐dimensional visualisation of muscle spindles in mouse soleus skeletal muscle in conjunction with the neurovascular bundle associated with it.