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Diabetes mellitus may affect short‐term outcome of Guillain‐Barré syndrome
Author(s) -
Peric Stojan,
Bozovic Ivo,
Bjelica Bogdan,
Berisavac Ivana,
Stojiljkovic Olivera,
Basta Ivana,
BeslacBumbasirevic Ljiljana,
RakocevicStojanovic Vidosava,
Lavrnic Dragana,
Stevic Zorica
Publication year - 2017
Publication title -
journal of the peripheral nervous system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 67
eISSN - 1529-8027
pISSN - 1085-9489
DOI - 10.1111/jns.12206
Subject(s) - medicine , diabetes mellitus , guillain barre syndrome , odds ratio , logistic regression , retrospective cohort study , pediatrics , nadir , affect (linguistics) , endocrinology , linguistics , philosophy , satellite , aerospace engineering , engineering
We sought to determine influence of diabetes mellitus on Guillain‐Barré syndrome (GBS) course and short‐term prognosis. Among the 257 GBS patients included in this retrospective study, diabetes mellitus was present in 17%. The degree of disability at admission and on discharge was assessed according to the GBS Disability Scale (mild disability = 0–3, severe disability = 4–6). Even after correction for age, diabetes mellitus was significantly associated with more severe disability at nadir (odds ratio, OR = 3.4, p < 0.05) and on discharge (OR = 2.0, p < 0.05). Linear regression analysis with multiple factors included showed that age and presence of diabetes were significant predictors of severe disability at nadir (adjusted R 2 = 0.21, p < 0.05), and on discharge (adjusted R 2 = 0.19, p < 0.05). The presence of diabetes mellitus affects short‐term prognosis of GBS, independent of age.