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Shared lesion correlates of semantic and letter fluency in post‐stroke aphasia
Author(s) -
Thye Melissa,
Szaflarski Jerzy P.,
Mirman Daniel
Publication year - 2021
Publication title -
journal of neuropsychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.85
H-Index - 37
eISSN - 1748-6653
pISSN - 1748-6645
DOI - 10.1111/jnp.12211
Subject(s) - fluency , aphasia , psychology , cognitive psychology , dissociation (chemistry) , univariate , lesion , neural correlates of consciousness , multivariate statistics , audiology , cognition , medicine , neuroscience , computer science , psychiatry , chemistry , mathematics education , machine learning
Lesion–symptom mapping studies have reported a temporal versus frontal dissociation between semantic and letter fluency, and mixed evidence regarding the role of white matter. Mass‐univariate and multivariate lesion–symptom mapping was used to identify regions associated with semantic and letter fluency deficits in post‐stroke aphasia. Multivariate LSM revealed broad networks including underlying white matter, and substantial overlap between both types of fluency, suggesting that semantic fluency and letter fluency largely rely on the same neural system. All data are available on OSF.