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Issue Information
Publication year - 2022
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.15406
Subject(s) - tropomyosin receptor kinase b , tropomyosin receptor kinase a , neurotrophin , trk receptor , tropomyosin receptor kinase c , low affinity nerve growth factor receptor , neuroscience , receptor , biology , microbiology and biotechnology , neurotrophic factors , biochemistry , platelet derived growth factor receptor , growth factor
Front cover Using neurons differentiated from human embryonic stem cells, Ateaque and coworkers studied neurotrophin signaling using wild‐type neurons (stained here for tubulin, green) as well as neurons lacking the BDNF receptor TrkB. These mutant neurons allowed Neurotrophin‐3 signaling to be examined in the absence of TrkB activation. Image content The image shows Tuj1 staining at x40 magnification, right side.Read the full article ‘ Selective activation and down‐regulation of Trk receptors by neurotrophins in human neurons co‐expressing TrkB and TrkC ’ by S. Ateaque, S. Merkouris, S. Wyatt, N. D. Allen, J. Xie, P. S. DiStefano, R. M. Lindsay and Y‐A. Barde (J. Neurochem. 2022, vol. 161 (6),pp. 463–477) on doi: 10.1111/jnc.15617