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Issue Cover (April 2021)
Publication year - 2021
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.15060
Subject(s) - neuroscience , postsynaptic potential , psychoanalysis , cover (algebra) , neurotransmitter , cognitive science , psychology , medicine , mechanical engineering , receptor , engineering , central nervous system
Front cover: The fundamental principle underlying brain communication is the tightly controlled release of chemical neurotransmitter in response to action potential stimulation. Neurotransmitter release occurs at presynaptic terminals. Proper presynaptic function is therefore critical for proper signal transduction, and dysfunction can cause pathophysiology. The current special issue presents summaries and updates on relevant aspects of presynaptic (dys‐)function in healthy homeostatis and disease. Image Content: Depicted are primary cultures of hippocampal neurons that have been transduced with a EGFP (green) expressing virus and then immunolabelled with both vGLUT (magenta) and PSD95 (cyan) to mark presynaptic and postsynaptic sites respectively.Read the full article ‘Preface to the Special Issue “Presynaptic Dysfunction and Diseaseˮ ’ K. J. Smillie, M. A. Cousin, S. L. Gordon ( J. Neurochem. 2021, vol. 157 (2), pp. 102–106) on doi: 10.1111/jnc.15319