Premium
Issue Cover (October 2020)
Publication year - 2020
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.14765
Subject(s) - olfactory bulb , olfactory system , neuroscience , tropism , virus , sensory system , biology , central nervous system , medicine , virology
Front cover: While the respiratory syncytium virus (RSV) is mainly known for the damage it causes in the respiratory tract, it could also impact the central nervous system. We explored globally the impact of RSV in the mouse nasal cavity and showed that RSV can infect olfactory sensory neurons, giving the virus access to the central nervous system by entering the olfactory bulb. Our study also yielded a 3D atlas of the nasal cavity in mice, providing tools to improve our understanding of virus tropism in the upper respiratory tract. Image content : The present image is a periodic acid–Schiff reaction (PAS)‐stained coronal section of the mice nasal cavity.Read the full article ‘Respiratory syncytial virus tropism for olfactory sensory neurons in mice’ by B. Bryche, M. Frétaud, A. Saint‐Albin Deliot, M. Galloux, L. Sedano, C. Langevin, D. Descamps, M.‐A. Rameix‐Welti, J.‐F, Eléouët, R. Le Goffic, N. Meunier, ( J. Neurochem. 2020, vol. 155 (2), pp. 137–153) on doi: 10.1111/jnc.14936