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Issue Cover (March 2019)
Publication year - 2019
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.14496
Subject(s) - lysosomal storage disorders , context (archaeology) , lysosome , batten disease , glial fibrillary acidic protein , front cover , dapi , neuroscience , pathology , biology , cover (algebra) , medicine , staining , immunohistochemistry , biochemistry , enzyme , mechanical engineering , engineering , paleontology , disease
Front cover: Understanding the nuances of glial‐neuron crosstalk in the context of lysosomal storage diseases is addressed by articles in this Special Issue and will be important for developing novel therapeutic approaches for this group of lysosomal disorders. The image shows co‐culture of primary mouse neurons (identified by staining for microtubule‐associated protein 2 (MAP2); pink) and astrocytes (identified by staining for glial fibrillary acidic protein (GFAP); green; nuclei are stained with diamidino‐2‐phenylindole (DAPI) isolated from a mouse model of juvenile neuronal ceroid lipofuscinosis (Cln3Δex7/8).Read the full article ‘ Lysosomal storage disorders: pathology within the lysosome and beyond’ by T. Kielian ( J. Neurochem. 2019, vol. 148 (5), pp. 568–572) on doi: 10.1111/jnc.14672