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Issue Cover (December 2017)
Publication year - 2017
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.13825
Subject(s) - astrocyte , glutamate receptor , microbiology and biotechnology , mechanism (biology) , cd31 , transporter , front cover , cover (algebra) , biology , neuroscience , chemistry , biochemistry , immunology , gene , immunohistochemistry , central nervous system , philosophy , receptor , mechanical engineering , engineering , epistemology
Front cover: Co‐culturing astrocytes (GFAP, green) with endothelial cells (CD31, yellow) increases cleaved Notch1 (NICD, red) in astrocytic nuclei and induces expression of the glial glutamate transporter GLT‐1. These results suggest a novel role for endothelial cells in the regulation of astrocytic function via a Notch‐dependent mechanism.Read the full article ‘Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT‐1 by a Notch‐dependent mechanism’ by M. L. Lee, Z. Martinez‐Lozada, E. N. Krizman and M. B. Robinson ( J. Neurochem . 2017, vol. 143(5), pp. 489–506) on doi: 10.1111/jnc.14135