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Issue Cover (December 2016)
Publication year - 2016
Publication title -
journal of neurochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.75
H-Index - 229
eISSN - 1471-4159
pISSN - 0022-3042
DOI - 10.1111/jnc.13344
Subject(s) - subventricular zone , allopregnanolone , neural stem cell , neuroactive steroid , parvalbumin , nestin , stimulation , neuroprotection , microbiology and biotechnology , progenitor cell , chemistry , neurogenesis , biology , neuroscience , biochemistry , stem cell , receptor , gabaa receptor
Front cover: Neural stem cells from the adult mouse subventricular zone labeled with antibodies against the intermediate filament protein nestin (red). Stained in green is the fluorescent thymidine analog EdU, incorporated into DNA during S‐phase in proliferating cells. Treatment with novel neurosteroid analogs stimulates proliferation of immature progenitor cells and protects against amyloid β‐toxicity.Read the full article ‘ Novel analogs of allopregnanolone show improved efficiency and specificity in neuroprotection and stimulation of proliferation ’ by M. Karout, M. Miesch, P. Geoffroy, S. Kraft, H.‐D. Hofmann, A. G. Mensah‐Nyagan and M. Kirsch (J. Neurochem. 2016, vol. 139 (5), pp. 782–794) on doi: 10.1111/jnc.13693