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Issue Cover (January 2016)

Publication year - 2016

Publication title -

journal of neurochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.75

H-Index - 229

eISSN - 1471-4159

pISSN - 0022-3042

DOI - 10.1111/jnc.13300

Subject(s) - neurofibromin 1 , neurofibromatosis , mitosis , metaphase , suppressor , microtubule , biology , aneuploidy , glioblastoma , microbiology and biotechnology , chromosome , cancer research , genetics , cancer , gene

Front cover : The photomicrographs show both the co‐localization of the glioblastoma tumor suppressor neurofibromin with mitotic microtubules and normally congressed chromosomes at metaphase in astrocytes. Neurofibromin depletion leads to aberrant chromosome congression, a possible mechanism for the generation of CIN/aneuploidy in neurofibromatosis patients who have a 5‐fold increase incidence of glioblastoma.Read the full article ‘ Nuclear import mechanism of neurofibromin for localization on the spindle and function in chromosome congression ’ by X. Koliou, C. Fedonidis, T. Kalpachidou and D. Mangoura ( J. Neurochem. 2016, vol. 136 (1), pp. 78–91) on doi: 10.1111/jnc.13401

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