The A‐B‐C for SOR ting APP

This Editorial highlights a study by Hermey and colleagues in the current issue of Journal of Neurochemistry. In their study, the authors provide novel insights into single‐nucleotide polymorphisms associated with Alzheimer's disease and linked to the SorCS1 gene, toward a better understanding of the interaction of sorting receptor proteins which physically interact with the amyloid‐beta protein precursor (APP). SorCS1, sortilin‐related VPS10 domain‐containing receptor 1; SorLA, sortilin‐related Receptor with A‐type Repeats.Read the full article ‘SorCS1 variants and amyloid precursor protein (APP) are co‐transported in neurons but only SorCS1c modulates anterograde APP transport’ on page 60.