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Hepatic lesions in captive owl monkeys ( Aotus infulatus ) with ultrasonographic “starry sky” liver
Author(s) -
de Souza Alex Junior Souza,
Coutinho Leandro Nassar,
Silva Wellington Bandeira da,
Imbeloni Aline Amaral,
Carneiro Liliane Almeida,
KanashiroGalo Luciane,
Hagen Stefano Carlo Filippo,
Malheiros Andreza Pinheiro,
Sá Lilian Rose Marques de
Publication year - 2021
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12535
Subject(s) - pathology , hemosiderosis , hepatitis , steatosis , medicine , parenchyma , biology
Background The “starry sky” (SK) liver is ultrasonographic pattern characterized by multiple hyperechogenic foci in hepatic parenchyma. The study aimed to characterize the microscopic hepatic lesions in captive owl monkeys with SK liver. Methods Thirty‐seven clinically healthy owl monkeys had their liver scanned and 18 of them had liver biopsy. Animals with SK and peliosis hepatis (PH) were subjected to immunohistochemical and molecular screening for Bartonella spp. Results SK liver occurred in 59.4% (22/37) of the owl monkeys. Biopsied animals showed steatosis, hydropic degeneration, hemosiderosis, PH, and multifocal granulomatous hepatitis. Two monkeys had SK, granulomatous hepatitis, and PH which were negative for Bartonella spp. Conclusions PH and granulomatous hepatitis associated with hepatocellular degenerative lesions may present as hyperechoic nodular liver lesions consisted of SK liver; therefore, concomitant occurrence of two lesions or more contributed to the hepatic SK pattern among owl monkeys and such cases might be clinically monitored.