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Comparative study of blood pressure and echocardiographic values of male cynomolgus macaques ( Macaca fascicularis )
Author(s) -
Orlov Sergey V.,
Panchenko Andrey V.,
Beresneva Olga N.,
Karalogly Dzhina D.,
Kucher Anatoly G.,
Ivanova Galina T.,
Parastaeva Marina M.,
Smirnov Alexey V.,
Kayukov Ivan G.,
Kulikov Aleksander N.
Publication year - 2021
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12520
Subject(s) - intracardiac injection , blood pressure , hemodynamics , macaque , medicine , cardiology , reference values , doppler echocardiography , rhesus macaque , physiology , pathology , biology , neuroscience , immunology , diastole
Background Primates represent a unique object for biomedical research, in particular in the field of physiology and pathology of the cardiovascular system. Echocardiography is the most important non‐invasive method for the intravital study of the heart structure and function, intracardiac and systemic haemodynamics. The available data on reference values of echocardiographic parameters in primates are limited. Methods We determined and described 29 structural and functional parameters in echocardiographic examination using B‐mode (two‐dimensional scanning), M‐mode (one‐dimensional scanning) and in various Doppler modes together with blood pressure in 17 male cynomolgus macaques with an average age of 5.7 ± 0.6 years. We compared available literature data on reference values of echocardiography in this species. Results and conclusions Echocardiographic values in cynomolgus macaques depend on age, sex composition and the anaesthesia method. There is lack of presentation in the published studies of complete list of parameters that can be obtained by echocardiographic examination.