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Histopathological kidney changes and myoglobinuria in neotropical non‐human primates attacked by dogs, Brazil
Author(s) -
Fernandes Natália Coelho Couto de Azevedo,
Nascimento Paloma Martins,
SánchezSarmiento Angélica M.,
Ressio Rodrigo A.,
Santos Cirqueira Cinthya,
Kanamura Cristina Takami,
Carvalho Júlia,
Silva Silvana Mello Pereira,
Peruchi Amanda Rezende,
Souza Junior Julio César,
Hirano Zelinda Maria Braga,
CatãoDias José Luiz
Publication year - 2020
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12456
Subject(s) - myoglobinuria , histopathology , stain , kidney , medicine , pathology , rhabdomyolysis , staining , surgery
Background Non‐human primates (NHPs) are susceptible to dogs’ attacks, events that may cause muscle damage along with stress, and could be in some extent compatible with capture myopathy, a syndrome that results in myoglobinuria and renal damage. Methods We aimed to evaluate by histopathology pre‐existing lesions and subsequent sequelae related to dogs’ attacks, acute tubular necrosis (ATN) and myoglobinuria, as well as the usefulness of Pearls Stain and IHC to diagnose it. Histopathology was performed in available organs, and sections of kidney submitted to Prussian blue stain and myoglobin immunohistochemistry. Results During January 2014—June 2016, 16/145 (11%) of NHPs received by Adolfo Lutz Institute, Brazil were reported as attacked by dogs. A high frequency of young and debilitated animals was found. Myoglobinuria was observed in more than half animals (9/16; 56.2%), from which (5/9; 55.5%) presented ATN. Conclusions Kidney lesions are plausible findings in NHPs attacked by dogs.