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In situ hybridization assay for the diagnosis of chagas myocarditis and orchitis in a rhesus macaque ( Macaca mulatta ): A case report
Author(s) -
DeLorenzo Megan,
Carias Elvira,
Mustonen Allison,
Gonzalez Olga,
Dick Edward J.,
Kumar Shyamesh
Publication year - 2019
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12406
Subject(s) - orchitis , in situ hybridization , rhesus macaque , trypanosoma cruzi , biology , myocarditis , macaque , virology , pathology , chagas disease , medicine , genetics , parasite hosting , paleontology , gene expression , world wide web , computer science , gene
We present the first documented case of Trypanosoma cruzi ‐induced orchitis in a rhesus macaque. Additionally, we describe an in situ hybridization–based assay to confirm T. cruzi infection in formalin‐fixed tissues.