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Electrocardiographic parameters of Sapajus libidinosus (SPIX, 1823) after chemical immobilization with tiletamine‐zolazepam
Author(s) -
La Salles Ana Yasha F.,
Andrade Jéssica K.,
Lemos Khelven K. A.,
Carreiro Artur da N.,
Souza Joyce G.,
Costa Tiago S. F.,
Reinaldo Maria Patrícia O. S.,
Souza Almir P.,
Menezes Danilo José A.
Publication year - 2019
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12403
Subject(s) - qrs complex , normal sinus rhythm , medicine , qt interval , sinus tachycardia , heart rate , sinus rhythm , anesthesia , t wave , cardiology , electrocardiography , blood pressure , atrial fibrillation
Background Tiletamine‐zolazepam is a widely used as an alternative chemical immobilization method in non‐human primates, with a safe application pathway and necessary relaxation. In order to determine the electrocardiographic parameters of Sapajus libidinosus after intramuscular tiletamine‐zolazepam administration at the dose of 5 mg/kg, nine animals were submitted to anesthesia. Methods The interpretation of the electrocardiogram determined: heart rate in bpm and heart rhythm, P wave, P‐R interval, R wave, QRS complex, T wave, Q‐T interval, corrected QT interval and electrical axis. The mean HR was 206 ± 32 bpm. Results The majority of the monkeys showed normal sinus rhythm, but one animal showed sinus tachycardia. The most commonly observed electrical axis was between +30° and +90°. Two animals presented bigger alterations in the tracing such as low amplitude QRS and T wave bigger than 1/4 of the R wave. Conclusions The administration of tiletamine‐zolazepam was safe and efficacious, with minimal cardiovascular effects.