Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney | Zendy

Uno Yasuhiro | Zendy; Shimizu Makiko | Zendy; Yoda Hiromi | Zendy; Yamazaki Hiroshi | Zendy

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Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney

Author(s) -

Uno Yasuhiro,

Shimizu Makiko,

Yoda Hiromi,

Yamazaki Hiroshi

Publication year - 2019

Publication title -

journal of medical primatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.31

H-Index - 42

eISSN - 1600-0684

pISSN - 0047-2565

DOI - 10.1111/jmp.12385

Subject(s) - flavin containing monooxygenase , monooxygenase , kidney , biology , macaque , flavin group , medicine , endocrinology , biochemistry , enzyme , cytochrome p450 , ecology

Flavin‐containing monooxygenase 1 ( FMO 1) largely remains to be characterized in cynomolgus macaque kidney. Immunoblotting showed expression of cynomolgus FMO 1 in kidneys where activities of FMO 1 (benzydamine N‐ oxygenation) were detected. No sex differences were observed in their contents or activities. These results suggest the functional role of cynomolgus FMO 1 in kidney.

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