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Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney
Author(s) -
Uno Yasuhiro,
Shimizu Makiko,
Yoda Hiromi,
Yamazaki Hiroshi
Publication year - 2019
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12385
Subject(s) - flavin containing monooxygenase , monooxygenase , kidney , biology , macaque , flavin group , medicine , endocrinology , biochemistry , enzyme , cytochrome p450 , ecology
Flavin‐containing monooxygenase 1 ( FMO 1) largely remains to be characterized in cynomolgus macaque kidney. Immunoblotting showed expression of cynomolgus FMO 1 in kidneys where activities of FMO 1 (benzydamine N‐ oxygenation) were detected. No sex differences were observed in their contents or activities. These results suggest the functional role of cynomolgus FMO 1 in kidney.