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Indirect activation of rhesus macaque ( Macaca mulatta ) NK cells in oral and mucosal draining lymph nodes
Author(s) -
Ram Daniel R.,
Kroll Kyle,
Reeves R. Keith
Publication year - 2018
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12371
Subject(s) - rhesus macaque , lymph , immunology , biology , innate immune system , macaque , immunity , immune system , medicine , pathology , neuroscience
The oral mucosae and draining lymph nodes are primary entry points for invading pathogens, particularly during immunosuppressive HIV / SIV infections. Innate immunity against oral stimuli, including natural killer ( NK ) cells, is understudied. Herein, we demonstrate functional NK cell responses to pathogen‐associated molecular patterns ( PAMP s) of potential oral pathogens in rhesus macaques.