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Effect of age on electrical nerve conduction in the somatosensory pathway and its correlation with somatometry and plasma concentrations of musculoskeletal enzymes in male rhesus monkeys ( Macaca mulatta ) held in captivity
Author(s) -
HernándezGodínez Braulio,
Poblano Adrián,
BonillaJaime Herlinda,
ArtegaSilva Marcela,
SánchezTorres Stephanie,
MondragónLozano Rodrigo,
IbáñezContreras Alejandra
Publication year - 2018
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12337
Subject(s) - somatosensory system , anatomy , forearm , lactate dehydrogenase , nerve conduction velocity , medicine , physiology , biology , neuroscience , enzyme , biochemistry
Background Somatosensory evoked potentials ( SEP s) make it possible to obtain functional data on the activity of somatosensory pathway. Objective To evaluate the ontogeny of electrical nerve conduction in male rhesus monkeys using SEP s in correlation with the development of the musculoskeletal system based on somatometry and musculoskeletal enzymes. Methods Somatosensory evoked potentials of the medial and tibial nerves were performed, and somatometric measurements were obtained: total length, arm and forearm length, and thigh and calf length. Analysis of the musculoskeletal enzymes, lactic dehydrogenase, and creatininase was conducted using blood samples in 20 rhesus monkeys divided into 5 groups. Results Statistical analysis manifested a delay in the appearance of latencies as age increased. Also evident was a strong, direct relation between the lengths and the value of the latencies of the SEP , together with an inverse relation between the musculoskeletal enzymes. Conclusions These findings contribute to standardizing this animal model in the neurophysiological sciences.