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CD 4+ Cell infiltration into subcutaneous adipose tissue is not indicative of productively infected cells during acute SHIV infection
Author(s) -
Hsu Denise C.,
Wegner Matthew D.,
Sunyakumthorn Piyanate,
Silsorn Decha,
Tayamun Sujitra,
Inthawong Dutsadee,
Kuncharin Yanin,
ImErbsin Rawiwan,
Ege Christine,
O'Connell Robert J.,
Michael Nelson L.,
Ndhlovu Lishomwa C.,
Vasan Sandhya
Publication year - 2017
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12298
Subject(s) - adipose tissue , infiltration (hvac) , subcutaneous adipose tissue , biology , immunology , rna , cell , endocrinology , gene , biochemistry , physics , thermodynamics
Limited longitudinal data exist on the effect of HIV on adipose tissue ( AT ). We found an increase in CD 4+ cells and detectable SHIV ‐ RNA in AT during acute SHIV infection. SHIV ‐ RNA + cells were rare, suggesting that AT is unlikely to be a major source of productively infected cells in SHIV infection.