Premium
Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies
Author(s) -
Yee JoAnn L.,
Grant Richard,
Van Rompay Koen K.,
Kuller LaRene,
Carpenter Amanda,
Watanabe Robin,
Huebner Rebeca,
Agricola Brian,
Smedley Jeremy,
Roberts Jeffrey A.
Publication year - 2017
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12295
Subject(s) - serology , virology , rhesus macaque , suspect , simian , macaque , biology , virus , immunology , artifact (error) , antibody , psychology , neuroscience , criminology
To better understand Simian betaretrovirus ( SRV ) seropositivity in virus‐negative macaques, we transfused blood from SRV ‐infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV 1‐5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV , or an endogenous virus.