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Fatal SV 40‐associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque
Author(s) -
Song M.,
Mulvihill M.S.,
Williams K.D.,
Collins B.H.,
Kirk A.D.
Publication year - 2018
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12285
Subject(s) - viremia , pneumonia , allotransplantation , virology , rhesus macaque , nephropathy , macaque , immunology , nephritis , polyomavirus infections , medicine , biology , virus , kidney , kidney transplantation , transplantation , bk virus , paleontology , diabetes mellitus , endocrinology
Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 ( SV 40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV 40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.