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Mucosal bacterial dissemination in a rhesus macaque model of experimental brucellosis
Author(s) -
RussellLodrigue Kasi E.,
Killeen Stephanie Z.,
Ficht Thomas A.,
Roy Chad J.
Publication year - 2018
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12282
Subject(s) - brucella melitensis , brucellosis , rhesus macaque , nonhuman primate , brucella , microbiology and biotechnology , biology , virology , macaque , saliva , immunology , evolutionary biology , paleontology , biochemistry
Abstract Animals were experimentally infected with Brucella melitensis via aerosol. B. melitensis was cultured from the saliva and vaginal vault of infected animals, corresponding to bacterial dissemination in other target tissues. This is the first report of bacterial dissemination to these mucosal surfaces in a non‐human primate model of brucellosis.