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Genetic diversity of Klebsiella pneumoniae isolates during an outbreak in a non‐human primate research colony
Author(s) -
Gozalo Alfonso S.,
Elkins William R.,
Lambert Lynn E.,
Stock Frida,
Thomas Marvin L.,
Woodward Ruth A.
Publication year - 2016
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12229
Subject(s) - outbreak , biology , primate , klebsiella pneumoniae , virology , genetic diversity , polymerase chain reaction , microbiology and biotechnology , pathogen , genetics , escherichia coli , gene , medicine , population , ecology , environmental health
Background Klebsiella pneumoniae can be a serious pathogen in non‐human primates, particularly Neotropical monkeys. Methods During a K. pneumoniae outbreak in an owl monkey research colony, 13 K. pneumoniae isolates were DNA fingerprinted by automated repetitive extragenic palindromic‐polymerase chain reaction and the profiles compared to isolates obtained from other non‐human primate species during the same time period and isolates from previous outbreaks. Results Eleven different types of K. pneumoniae were circulating in the owl monkey colony at the time of the outbreak. When comparing owl monkey isolates relatedness to previous colony outbreak isolates and squirrel monkey and capuchin monkey isolates, all were different. Conclusions These results agree with recent reports where K. pneumoniae nosocomial isolates in hospital settings can have high genetic diversity, and multiple strains can be circulating simultaneously. This potential genetic diversity should be considered when designing strategies for controlling K. pneumoniae outbreaks in captive non‐human primate colonies.