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Microdissection approaches in tuberculosis research
Author(s) -
Hudock Teresa A.,
Lackner Andrew A.,
Kaushal Deepak
Publication year - 2014
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12141
Subject(s) - microdissection , tuberculosis , mycobacterium tuberculosis , pathogen , biology , granuloma , lesion , laser capture microdissection , latent tuberculosis , computational biology , pathology , microbiology and biotechnology , immunology , medicine , genetics , gene , gene expression
Mycobacterium tuberculosis , a globally significant pathogen, results in active or latent tuberculosis. The granuloma is the characteristic lesion that offers insight into host–pathogen interactions in these distinct states. Microdissection provides a way to isolate and consequently investigate specific tissue sections. We review various techniques available and in use.