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Nodular lymphoid hyperplasia of the colon in a vervet monkey ( Cholorocebous aethiops )
Author(s) -
Hablolvarid M.H.
Publication year - 2014
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12133
Subject(s) - pathology , simian , hyperplasia , lymphoid hyperplasia , gastrointestinal tract , lymphatic system , small intestine , medicine , biology , virus , immunology , lymphoma
Background Diffuse nodular lymphoid hyperplasia ( DNLH ) of gastrointestinal tract is regarded as a very rare disease in the adult population. It is characterized by presence of diffuse detectable small polypoid masses distributed in the small intestine, colon, or both. Methods A 6‐year‐old male in captivity suddenly died, due to myocardial infarction. During routine necropsy procedure, incidentally, numerous tan, sessile polyps, up to 0.2 cm were noticed in all segments of the colon. Results Histopathological and immunohistochemical examination revealed polypoid masses as nodular lymphoid hyperplasia ( NLH ), comparable with DNLH of the colon in human. Conclusions In this article, the author has tried to introduce some immunosuppresive (e.g., simian retrovirus type D ( SRV ), simian immunodeficiency virus ( SIV )) and opportunistic viruses (e.g., lymphocryptovirus, γ‐herpesvirus, adenovirus), as well as, primary and opportunistic bacteria (e.g., Yersinia psedotuberculosis , and Helicobacter spp.) that may trigger benign reactive process, lymphoid hyperplasia, in non‐human primates ( NHP s) in captivity.