Premium
Genetic diversity and population structure of long‐tailed macaque ( Macaca fascicularis ) populations in Peninsular Malaysia
Author(s) -
Nikzad Sonia,
Tan Soon Guan,
Yong Seok Yien Christina,
Ng Jillian,
Alitheen Noorjahan Banu,
Khan Razib,
RovieRyan Jeffrine J.,
Valdiani Alireza,
Khajeaian Parastoo,
Kanthaswamy Sree
Publication year - 2014
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12130
Subject(s) - genetic diversity , biology , genetic structure , population , macaque , mainland , zoology , geographical distance , genetic variation , evolutionary biology , ecology , demography , genetics , sociology , gene
Background The genetic diversity and structure of long‐tailed macaques ( Macaca fascicularis ) in Peninsular Malaysia, a widely used non‐human primate species in biomedical research, have not been thoroughly characterized. Methods Thirteen sites of wild populations of long‐tailed macaques representing six states were sampled and analyzed with 18 STR markers. Results The Sunggala and Penang Island populations showed the highest genetic diversity estimates, while the Jerejak Island population was the most genetically discrete due to isolation from the mainland shelf. Concordant with pairwise F st estimates, STRUCTURE analyses of the seven PCA ‐correlated clusters revealed low to moderate differentiation among the sampling sites. No association between geographic and genetic distances exists, suggesting that the study sites, including island study sites, are genetically if not geographically contiguous. Conclusions The status of the genetic structure and composition of long‐tailed macaque populations require further scrutiny to develop this species as an important animal model in biomedical research.