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Outbreak of pathogenic E scherichia coli in an outdoor‐housed non‐human primate colony
Author(s) -
Kolappaswamy K.,
Nazareno J.,
Porter W.P.,
Klein H.J.
Publication year - 2014
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12099
Subject(s) - feces , diarrhea , outbreak , microbiology and biotechnology , biology , virology , acute diarrhea , escherichia coli , medicine , immunology , biochemistry , gene
Background Pathogenic E scherichia coli has been identified as an etiologic agent in humans causing acute diarrhea or even death but has been rarely reported in non‐human primates ( NHP ). An outbreak of diarrhea occurred in an outdoor‐housed NHP colony over a period of 2 months with an attack rate of 29%. Methods Bacterial culture and PCR were performed on the fecal specimens to identify enteroinvasive E. coli ( EIEC ) and Enterohemorrhagic E. coli ( EHEC ) in the NHP s. Results By random sampling of 10% of fecal samples of diarrheal cases, four cases of EIEC in rhesus macaques and two cases of EHEC in cynomolgus macaques were confirmed. Conclusion This is the first time EIEC and EHEC have been reported in NHP s associated with diarrhea. The primary source of infection could not be determined.