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Changes in blood parameters in rhesus monkeys ( Macaca mulatta ) during the first trimester of gestation
Author(s) -
IbáñezContreras Alejandra,
HernándezGodínez Braulio,
ReyesPantoja Sergio A.,
JiménezGarcía Andrea,
SolísChavéz Salvador A.,
SuarezGutiérrez Rodrigo,
GálvanMontaño Alfonso
Publication year - 2013
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/jmp.12052
Subject(s) - hematology , gestation , physiology , pregnancy , reference range , first trimester , medicine , reproductive biology , obstetrics , andrology , bilirubin , second trimester , significant difference , biology , genetics , lactation
Background Regarding the good practice in the laboratory work, it is essential to have a broad spectrum of biochemical and hematological references in pregnant females to determine the health status of the colony. Objective To establish reference values to reveal changes in hematology and blood chemistry in pregnant rhesus monkeys ( M acaca mulatta ) in their first trimester of pregnancy. Methods Twenty‐eight females in reproductive stage were used, divided into two groups: 14 pregnant macaques in their first trimester and 14 non‐pregnant used as the control group. Blood samples were collected for the hematological test and blood chemistry. Results The results showed significant difference in the blood chemistry for the following parameters: glucose, total bilirubin, and total protein. The hematological evaluation revealed significant difference in leukocytes and neutrophils. Conclusions These findings offer a reference range and provide a basis for improvement in techniques and refinement of clinical processes in these specimens.